Molecular weight (DA)
90kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF19. AA range:251-300
Specificity
ARHGEF19 Polyclonal Antibody detects endogenous levels of ARHGEF19 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008],
Function
function:Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH3 domain.,
Protein name
Rho guanine nucleotide exchange factor 19
Other name
ARHGEF19; Rho guanine nucleotide exchange factor 19; Ephexin-2
Human protein sequence Database
Q8IW93
Mouse protein sequence database
Q8BWA8
Rat protein sequence database
Tissue expression
Colon,Pancreas,Tongue,