Immunogen
The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470
Specificity
GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
Function
similarity:Belongs to the GTP-binding elongation factor family. LepA subfamily.,
Protein name
Translation factor GUF1 mitochondrial
Other name
GUF1; Translation factor GUF1; mitochondrial; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase
Human protein sequence Database
Q8N442
Mouse protein sequence database
Q8C3X4
Rat protein sequence database
Cellular localization
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
Tissue expression
Brain,Colon,Lung adenocarcinoma,Teratocarcinoma,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车