Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF17. AA range:431-480
Specificity
p164-RhoGEF Polyclonal Antibody detects endogenous levels of p164-RhoGEF protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.,similarity:Contains 1 DH (DBL-homology) domain.,tissue specificity:Highly expressed in the heart.,
Function
function:Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.,similarity:Contains 1 DH (DBL-homology) domain.,tissue specificity:Highly expressed in the heart.,
Protein name
Rho guanine nucleotide exchange factor 17
Other name
ARHGEF17; KIAA0337; TEM4; Rho guanine nucleotide exchange factor 17; 164 kDa Rho-specific guanine-nucleotide exchange factor; p164-RhoGEF; p164RhoGEF; Tumor endothelial marker 4
Human protein sequence Database
Q96PE2
Mouse protein sequence database
Q80U35
Rat protein sequence database
Cellular localization
cytosol,
Tissue expression
Highly expressed in the heart.
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