Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213
Specificity
Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010],
Function
function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4.,
Protein name
Ras-related protein Rab-11B
Other name
RAB11B; YPT3; Ras-related protein Rab-11B; GTP-binding protein YPT3
Fields
>>Endocytosis;>>AMPK signaling pathway;>>Vasopressin-regulated water reabsorption;>>Influenza A
Human protein sequence Database
Q15907
Mouse protein sequence database
P46638
Rat protein sequence database
O35509
Cellular localization
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus. .
Tissue expression
B-cell lymphoma,Brain,Cerebellum,Muscle,
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