Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB40B. AA range:229-278
Specificity
Rab 40B Polyclonal Antibody detects endogenous levels of Rab 40B protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008],
Function
domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,
Protein name
Ras-related protein Rab-40B
Other name
RAB40B; SEC4L; Ras-related protein Rab-40B; SOCS box-containing protein RAR; Protein Rar
Human protein sequence Database
Q12829
Mouse protein sequence database
Q8VHP8
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
Tissue expression
Brain,Hippocampus,
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