Immunogen
The antiserum was produced against synthesized peptide derived from human RAB41. AA range:115-164
Specificity
Rab 41 Polyclonal Antibody detects endogenous levels of Rab 41 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010],
Function
similarity:Belongs to the small GTPase superfamily. Rab family.,
Protein name
Ras-related protein Rab-41
Other name
RAB41; Ras-related protein Rab-41
Human protein sequence Database
Q5JT25
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . punctate localization concentrated in ruffled regions at the cell periphery.
Tissue expression
Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver.
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