Molecular weight (DA)
27kD
Immunogen
Synthesized peptide derived from Rab 26 . at AA range: 180-256
Specificity
Rab 26 Polyclonal Antibody detects endogenous levels of Rab 26 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010],
Function
function:Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Predominantly expressed in brain.,
Protein name
Ras-related protein Rab-26
Other name
RAB26; Ras-related protein Rab-26
Human protein sequence Database
Q9ULW5
Mouse protein sequence database
Q504M8
Rat protein sequence database
P51156
Cellular localization
Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Not localized at the plasma membrane (By similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location. .
Tissue expression
Predominantly expressed in brain.
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