Molecular weight (DA)
54kD
Immunogen
The antiserum was produced against synthesized peptide derived from human KCNS2. AA range:197-246
Specificity
KV9.2 Polyclonal Antibody detects endogenous levels of KV9.2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Potassium channel subunit. Modulates channel activity and reduces the ion flow.,similarity:Belongs to the potassium channel family. S subfamily.,subcellular location:May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.,subunit:Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins.,
Function
domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Potassium channel subunit. Modulates channel activity and reduces the ion flow.,similarity:Belongs to the potassium channel family. S subfamily.,subcellular location:May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.,subunit:Heteromultimer with KCNB1 and with KCNB2. Does not form homomultimers. Might also bind to other channel proteins.,
Protein name
Potassium voltage-gated channel subfamily S member 2
Other name
KCNS2; KIAA1144; Potassium voltage-gated channel subfamily S member 2; Delayed-rectifier K(+) channel alpha subunit 2; Voltage-gated potassium channel subunit Kv9.2
Human protein sequence Database
Q9ULS6
Mouse protein sequence database
O35174
Rat protein sequence database
Q9ER26
Cellular localization
Cell membrane ; Multi-pass membrane protein . May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2. .
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