Cdc40 Polyclonal Antibody

Polyclonal antibody

Specification

BYab-16685

50UL $180 100UL $255
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Product introduction Experimental scheme Citation Related products

Product introduction>

Host

Reactiveness

Use

Molecular weight (DA)

66kD

Immunogen

The antiserum was produced against synthesized peptide derived from human CDC40. AA range:179-228

Specificity

Cdc40 Polyclonal Antibody detects endogenous levels of Cdc40 protein.

Source

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Dilution rate

WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200

Purification process (Immunogen)

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Background

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008],

Function

function:Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.,similarity:Contains 7 WD repeats.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,

Gene Name

CDC40

Protein name

Pre-mRNA-processing factor 17

Abbreviation

Cdc40

Other name

CDC40; EHB3; PRP17; PRPF17; Pre-mRNA-processing factor 17; Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17

Fields

>>Spliceosome

Human gene ID

51362

Human protein sequence Database

O60508

Mouse gene ID

71713

Mouse protein sequence database

Q9DC48

Rat gene ID

Rat protein sequence database

Cellular localization

Nucleus . Nucleus speckle .

Tissue expression

Brain,Cervix carcinoma,Colon,Colon epithelium,Epithelium,Trachea,

Storage

-20°C/1 year

Experimental scheme>

Procedure

Cdc40 Polyclonal Antibody

BYab-16685

Product introduction>

Host

Reactiveness

Use

Molecular weight (DA)

Immunogen

Specificity

Source

Formulation

Dilution rate

Purification process (Immunogen)

Concentration

Background

Function

Gene Name

Protein name

Abbreviation

Other name

Fields

Human gene ID

Human protein sequence Database

Mouse gene ID

Mouse protein sequence database

Rat gene ID

Rat protein sequence database

Cellular localization

Tissue expression

Storage

Experimental scheme>

Citation(0)>

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Cdc40 Polyclonal Antibody

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