Molecular weight (DA)
43kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CDK10. AA range:51-100
Specificity
Cdk10 Polyclonal Antibody detects endogenous levels of Cdk10 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,
Protein name
Cyclin-dependent kinase 10
Other name
CDK10; Cyclin-dependent kinase 10; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE
Human protein sequence Database
Q15131
Mouse protein sequence database
Q3UMM4
Rat protein sequence database
Q4KM47
Cellular localization
Cytoplasm, cytoskeleton, cilium basal body .
Tissue expression
Brain,Colon,Kidney,Lung,
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