Immunogen
The antiserum was produced against synthesized peptide derived from human CKS2. AA range:1-50
Specificity
Cks2 Polyclonal Antibody detects endogenous levels of Cks2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
CDC28 protein kinase regulatory subunit 2(CKS2) Homo sapiens CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. [provided by RefSeq, Jul 2008],
Function
function:Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.,similarity:Belongs to the CKS family.,subunit:Forms an homohexamer that can probably bind six kinase subunits.,
Protein name
Cyclin-dependent kinases regulatory subunit 2
Other name
CKS2; Cyclin-dependent kinases regulatory subunit 2; CKS-2
Fields
>>Pathways in cancer;>>Small cell lung cancer
Human protein sequence Database
P33552
Mouse protein sequence database
P56390
Rat protein sequence database
Cellular localization
cyclin-dependent protein kinase holoenzyme complex,SCF ubiquitin ligase complex,
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