Molecular weight (DA)
10kD
Immunogen
Synthesized peptide derived from human LSM5
Specificity
This antibody detects endogenous levels of LSM5 at Human, Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, and 0.2089% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) . The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA .
Protein name
U6 snRNA-associated Sm-like protein LSm5
Human protein sequence Database
Q9Y4Y9
Mouse protein sequence database
P62322
Rat protein sequence database
Cellular localization
Nucleus .
Storage
’-15°C to -25°C/1 year(Do not lower than -25°C)