Molecular weight (DA)
Molecular Weight
Calculated MW: 16 kDa; Observed MW: 12 kDa
Immunogen
A synthesized peptide derived from human HBG1/2
Dilution rate
WB: 1/500-1/1000
Purification process (Immunogen)
Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008],
Abbreviation
Gamma 1 globin;Gamma 2 globin;Gamma A hemoglobin; Gamma globin; Hb FAgamma; Hb F Ggamma; HBG1; HBG2:HBGA: HBGR
Human gene ID
SwissProt ID
P69891/P69892
Human protein sequence Database
Gene ID
3047/3048
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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