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Rat Anti-Mouse CD86 mAb (PE/TR)

Refer to | for labeled antibodies

Specification

BYab-17757

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
A synthesized peptide derived from Mouse CD86
Specificity
Source
Formulation
Dilution rate
FC: 5μL per test for million cells or whole blood in 100 μL volume.
Purification process (Immunogen)
Concentration
Background
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Function
Gene Name
Mouse CD86
Protein name
Abbreviation
Other name
T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1
Fields
Human gene ID
SwissProt ID P42082
Human protein sequence Database
Gene ID 12524
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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Rat Anti-Mouse CD86 mAb (PE/TR)

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