Molecular weight (DA)
Molecular Weight
Calculated MW: 82 kDa; Observed MW: 82 kDa
Clonality
Immunogen
Purified recombinant fragment of human DNM1L expressed in E. Coli.
Dilution rate
WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Purification process (Immunogen)
Background
The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Other name
DNM1L; DLP1; DRP1; Dynamin-1-like protein; Dnm1p/Vps1p-like protein; DVLP; Dynamin family member proline-rich carboxyl-terminal domain less; Dymple; Dynamin-like protein; Dynamin-like protein 4; Dynamin-like protein IV; HdynIV; Dynamin-rela
Human gene ID
SwissProt ID
O00429
Human protein sequence Database
Gene ID
10059
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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