Molecular weight (DA)
Molecular Weight
Calculated MW: 71 kDa; Observed MW: 55 kDa
Immunogen
A synthesized peptide derived from human TXNRD1
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Purification process (Immunogen)
Background
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Other name
TR; TR1; TXNR; TRXR1; GRIM-12
Human gene ID
SwissProt ID
Q16881
Human protein sequence Database
Gene ID
7296
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles