Molecular weight (DA)
Molecular Weight
Calculated MW: 15 kDa; Observed MW: 15 kDa
Immunogen
A synthetic peptide of human Histone H2A.X
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Purification process (Immunogen)
Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Other name
H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X
Human gene ID
SwissProt ID
P16104
Human protein sequence Database
Gene ID
3014
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.