Molecular weight (DA)
Molecular Weight
Calculated MW: 84 kDa; Observed MW: 84 kDa
Immunogen
A synthesized peptide derived from human NAK/TBK1 (N-term)
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Purification process (Immunogen)
Background
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.
Other name
TBK1; NAK; Serine/threonine-protein kinase TBK1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1
Human gene ID
SwissProt ID
Q9UHD2
Human protein sequence Database
Gene ID
29110
Mouse protein sequence database
Rat protein sequence database
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.