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elF4E Rabbit mAb

Refer to | for labeled antibodies

Specification

BYab-17916

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Molecular Weight Calculated MW: 25 kDa; Observed MW: 25 kDa
Immunogen
A synthetic peptide of human eIF4E
Specificity
Source
Formulation
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Purification process (Immunogen)
Concentration
Background
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
Function
Gene Name
EIF4E
Protein name
Abbreviation
Other name
EIF4E; EIF4EL1;EIF4F; Eukaryotictranslation initiation factor 4E; elF-4E; elF4EelF-4F 25 kDa subunit; mRNA cap-bindingprotein
Fields
Human gene ID
SwissProt ID P06730
Human protein sequence Database
Gene ID 1977
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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elF4E Rabbit mAb

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