Molecular weight (DA)
10kD
Immunogen
Synthesized peptide derived from human TIMM13
Specificity
This antibody detects endogenous levels of TIMM13 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Gene Name
TIMM13 TIM13B TIMM13A TIMM13B
Protein name
Mitochondrial import inner membrane translocase subunit Tim13
Human protein sequence Database
Q9Y5L4
Mouse protein sequence database
P62075
Rat protein sequence database
P62076
Cellular localization
Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .
Tissue expression
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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