Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from human GP73/GOLPH2
Specificity
This antibody detects endogenous levels of GP73/GOLPH2 at Human, Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Unknown. Cellular response protein to viral infection.
Gene Name
GOLM1 C9orf155 GOLPH2 PSEC0242 UNQ686/PRO1326
Protein name
Golgi membrane protein 1 (Golgi membrane protein GP73) (Golgi phosphoprotein 2)
Human protein sequence Database
Q8NBJ4
Mouse protein sequence database
Q91XA2
Rat protein sequence database
Cellular localization
Golgi apparatus, cis-Golgi network membrane ; Single-pass type II membrane protein . Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption.
Tissue expression
Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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