Molecular weight (DA)
94kD
Immunogen
Synthesized peptide derived from human TTC7A
Specificity
This antibody detects endogenous levels of TTC7A at Human, Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Function
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane . The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions (By similarity).
Gene Name
TTC7A KIAA1140 TTC7
Protein name
Tetratricopeptide repeat protein 7A (TPR repeat protein 7A
Human protein sequence Database
Q9ULT0
Mouse protein sequence database
Q8BGB2
Rat protein sequence database
Cellular localization
Cytoplasm . Cell membrane . Localizes to the cytosol and is recruited to the plasma membrane following interaction with EFR3 (EFR3A or EFR3B). .
Tissue expression
Expressed in epithelial cells of the intestine, thymus, and pancreas (at protein level).
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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