Molecular weight (DA)
80kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MDM1. AA range:665-714
Specificity
MDM1 Polyclonal Antibody detects endogenous levels of MDM1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
Function
similarity:Belongs to the MDM1 family.,
Protein name
Nuclear protein MDM1
Other name
MDM1; Nuclear protein MDM1
Human protein sequence Database
Q8TC05
Mouse protein sequence database
Q9D067
Rat protein sequence database
Q5PQN4
Cellular localization
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localizes to the centriole lumen. .
Tissue expression
Brain,Epithelium,Prostate,Testis,Trachea,
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