Molecular weight (DA)
122kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
PDE3B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,enzyme regulation:Inhibited by cGMP.,function:May play a role in fat metabolism.,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,tissue specificity:Abundant in adipose tissues.,
Function
catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,enzyme regulation:Inhibited by cGMP.,function:May play a role in fat metabolism.,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,tissue specificity:Abundant in adipose tissues.,
Protein name
cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)
Fields
>>Purine metabolism;>>Metabolic pathways;>>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Apelin signaling pathway;>>Insulin signaling pathway;>>Progesterone-mediated oocyte maturation;>>Glucagon signaling pathway;>>Regulation of lipolysis in adipocytes;>>Renin secretion;>>Morphine addiction
Human protein sequence Database
Q13370
Mouse protein sequence database
Q61409
Rat protein sequence database
Q63085
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Abundant in adipose tissues.
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