Molecular weight (DA)
65kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CPNE8. AA range:11-60
Specificity
Copine 8 Polyclonal Antibody detects endogenous levels of Copine 8 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
copine 8(CPNE8) Homo sapiens Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008],
Function
function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the copine family.,similarity:Contains 1 VWFA domain.,similarity:Contains 2 C2 domains.,
Other name
CPNE8; Copine-8; Copine VIII
Human protein sequence Database
Q86YQ8
Mouse protein sequence database
Q9DC53
Rat protein sequence database
Cellular localization
extracellular exosome,
Tissue expression
Brain,Hippocampus,
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