Molecular weight (DA)
64kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RABEP2. AA range:353-402
Specificity
Rabaptin-5β Polyclonal Antibody detects endogenous levels of Rabaptin-5β protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Plays a role in membrane trafficking and in homotypic early endosome fusion.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding.,
Function
function:Plays a role in membrane trafficking and in homotypic early endosome fusion.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding.,
Protein name
Rab GTPase-binding effector protein 2
Other name
RABEP2; RABPT5B; Rab GTPase-binding effector protein 2; Rabaptin-5beta
Human protein sequence Database
Q9H5N1
Mouse protein sequence database
Q91WG2
Rat protein sequence database
Q62835
Cellular localization
Cytoplasm . Early endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body .
Tissue expression
Hepatoma,Mammary gland,Testis,
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