Molecular weight (DA)
43kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Fra-2. AA range:271-320
Specificity
FOSL2 Polyclonal Antibody detects endogenous levels of FOSL2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014],
Function
similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,
Protein name
Fos-related antigen 2
Other name
FOSL2; FRA2; Fos-related antigen 2; FRA-2
Fields
>>Osteoclast differentiation
Human protein sequence Database
P15408
Mouse protein sequence database
P47930
Rat protein sequence database
P51145
Cellular localization
Nucleus .
Tissue expression
Endothelial cell,Epithelium,Lung,
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