Molecular weight (DA)
22kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RCL. AA range:1-50
Specificity
RCL Polyclonal Antibody detects endogenous levels of RCL protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008],
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role during cellular proliferation and c-Myc-mediated transformation.,tissue specificity:Expression is elevated in lymphoid cells that overexpress c-Myc.,
Protein name
Deoxyribonucleoside 5'-monophosphate N-glycosidase
Other name
RCL; C6orf108; Deoxyribonucleoside 5'-monophosphate N-glycosidase; c-Myc-responsive protein Rcl
Human protein sequence Database
O43598
Mouse protein sequence database
Q80VJ3
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus .
Tissue expression
Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers.
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