Molecular weight (DA)
53kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB3IP. AA range:257-306
Specificity
RAB3IP Polyclonal Antibody detects endogenous levels of RAB3IP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the SEC2 family.,subcellular location:Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus.,subunit:Interacts with the N-terminal region of SSX2. Interacts with RAB3A and RAB3D.,tissue specificity:Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.,
Function
similarity:Belongs to the SEC2 family.,subcellular location:Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus.,subunit:Interacts with the N-terminal region of SSX2. Interacts with RAB3A and RAB3D.,tissue specificity:Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.,
Protein name
Rab-3A-interacting protein
Other name
RAB3IP; RABIN8; Rab-3A-interacting protein; Rab3A-interacting protein; Rabin-3; SSX2-interacting protein
Human protein sequence Database
Q96QF0
Mouse protein sequence database
Q68EF0
Rat protein sequence database
Q62739
Cellular localization
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton . Cell projection, lamellipodium. Vesicle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. .
Tissue expression
Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.
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