Molecular weight (DA)
84kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RFX3. AA range:641-690
Specificity
RFX3 Polyclonal Antibody detects endogenous levels of RFX3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013],
Function
function:Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.,similarity:Belongs to the RFX family.,
Protein name
Transcription factor RFX3
Other name
RFX3; Transcription factor RFX3; Regulatory factor X 3
Human protein sequence Database
P48380
Mouse protein sequence database
P48381
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Muscle,Testis,