Molecular weight (DA)
57kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SFRS4. AA range:111-160
Specificity
SRp75 Polyclonal Antibody detects endogenous levels of SRp75 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009],
Function
function:A probable role in alternative splice site selection during pre-mRNA splicing.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN.,
Protein name
Serine/arginine-rich splicing factor 4
Other name
SRSF4; SFRS4; SRP75; Serine/arginine-rich splicing factor 4; Pre-mRNA-splicing factor SRP75; SRP001LB; Splicing factor; arginine/serine-rich 4
Fields
>>Spliceosome;>>Herpes simplex virus 1 infection
Human protein sequence Database
Q08170
Mouse protein sequence database
Q8VE97
Rat protein sequence database
Cellular localization
Nucleus speckle .
Tissue expression
Aorta endothelial cell,Cerebrum,Epithelium,Lymph,
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