Molecular weight (DA)
101kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TF3C3. AA range:101-150
Specificity
TFIIIC102 Polyclonal Antibody detects endogenous levels of TFIIIC102 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function
function:Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.,similarity:Contains 11 TPR repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1 and TBP.,
Protein name
General transcription factor 3C polypeptide 3
Other name
GTF3C3; General transcription factor 3C polypeptide 3; Transcription factor IIIC 102 kDa subunit; TFIIIC 102 kDa subunit; TFIIIC102; Transcription factor IIIC subunit gamma; TF3C-gamma
Human protein sequence Database
Q9Y5Q9
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Amygdala,Bone marrow,Hepatoma,Lymph,Placenta,
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