Molecular weight (DA)
33kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TRA-2 alpha. AA range:221-270
Specificity
Tra-2α Polyclonal Antibody detects endogenous levels of Tra-2α protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],
Function
function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.,PTM:Phosphorylated in the RS domains.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30.,
Protein name
Transformer-2 protein homolog alpha
Other name
TRA2A; Transformer-2 protein homolog alpha; TRA-2 alpha; TRA2-alpha; Transformer-2 protein homolog A
Fields
>>Spliceosome;>>Alcoholic liver disease
Human protein sequence Database
Q13595
Mouse protein sequence database
Q6PFR5
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Cervix carcinoma,Epithelium,Hepatocyte,Lung,Testis,Uterus,
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