Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TSSC1. AA range:291-340
Specificity
TSSC1 Polyclonal Antibody detects endogenous levels of TSSC1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008],
Function
similarity:Contains 5 WD repeats.,
Protein name
Protein TSSC1
Other name
TSSC1; Protein TSSC1; Tumor-suppressing STF cDNA 1 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein
Human protein sequence Database
Q53HC9
Mouse protein sequence database
Q8K0G5
Rat protein sequence database
Q5PPK9
Cellular localization
Golgi apparatus, trans-Golgi network .
Tissue expression
Cerebellum,Colon,
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