Immunogen
The antiserum was produced against synthesized peptide derived from human TSH2. AA range:811-860
Specificity
TSHZ2 Polyclonal Antibody detects endogenous levels of TSHZ2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Transcriptional regulator involved in developmental processes .,PTM:Sumoylated.,sequence caution:The sequence differs from that shown due translation of a 3'-UTR region.,similarity:Belongs to the teashirt C2H2-type zinc-finger protein family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 5 C2H2-type zinc fingers.,
Function
function:Transcriptional regulator involved in developmental processes .,PTM:Sumoylated.,sequence caution:The sequence differs from that shown due translation of a 3'-UTR region.,similarity:Belongs to the teashirt C2H2-type zinc-finger protein family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 5 C2H2-type zinc fingers.,
Protein name
Teashirt homolog 2
Other name
TSHZ2; C20orf17; TSH2; ZNF218; Teashirt homolog 2; Ovarian cancer-related protein 10-2; OVC10-2; Zinc finger protein 218
Human protein sequence Database
Q9NRE2
Mouse protein sequence database
Q68FE9
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.
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