Molecular weight (DA)
25kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AK5. AA range:391-440
Specificity
AK5 Polyclonal Antibody detects endogenous levels of AK5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
adenylate kinase 5(AK5) Homo sapiens This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + AMP = 2 ADP.,function:Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP.,similarity:Belongs to the adenylate kinase family.,subunit:Monomer.,tissue specificity:Brain specific.,
Protein name
Adenylate kinase isoenzyme 5
Other name
AK5; Adenylate kinase isoenzyme 5; AK 5; ATP-AMP transphosphorylase 5
Fields
>>Purine metabolism;>>Thiamine metabolism;>>Metabolic pathways;>>Nucleotide metabolism;>>Biosynthesis of cofactors
Human protein sequence Database
Q9Y6K8
Mouse protein sequence database
Q920P5
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Brain specific.
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