Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CA6. AA range:231-280
Specificity
CA VI Polyclonal Antibody detects endogenous levels of CA VI protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008],
Function
catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide. Its role in saliva is unknown.,similarity:Belongs to the alpha-carbonic anhydrase family.,tissue specificity:Major constituent of saliva.,
Protein name
Carbonic anhydrase 6
Other name
CA6; Carbonic anhydrase 6; Carbonate dehydratase VI; Carbonic anhydrase VI; CA-VI; Salivary carbonic anhydrase; Secreted carbonic anhydrase
Fields
>>Nitrogen metabolism;>>Metabolic pathways
Human protein sequence Database
P23280
Mouse protein sequence database
P18761
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Major constituent of saliva.
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