Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2W1. AA range:311-360
Specificity
CYP2W1 Polyclonal Antibody detects endogenous levels of CYP2W1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. [provided by RefSeq, Jul 2008],
Function
cofactor:Heme group.,similarity:Belongs to the cytochrome P450 family.,
Protein name
Cytochrome P450 2W1
Other name
CYP2W1; Cytochrome P450 2W1; CYPIIW1
Fields
>>Retinol metabolism;>>Metabolic pathways
Human protein sequence Database
Q8TAV3
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Endoplasmic reticulum lumen . Cell membrane . Microsome membrane . About 8% are expressed on the cell surface. .
Tissue expression
Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors.
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