Molecular weight (DA)
27kD
Immunogen
The antiserum was produced against synthesized peptide derived from human DHRS2. AA range:111-160
Specificity
DHRS2 Polyclonal Antibody detects endogenous levels of DHRS2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May inhibit cell replication either by catalyzing the oxidation of estrogen and androgen or by converting cortisone in cortisol.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
Function
function:May inhibit cell replication either by catalyzing the oxidation of estrogen and androgen or by converting cortisone in cortisol.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
Protein name
Dehydrogenase/reductase SDR family member 2
Other name
DHRS2; Dehydrogenase/reductase SDR family member 2; Dicarbonyl reductase HEP27; Protein D
Human protein sequence Database
Q13268
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Mitochondrion matrix. Nucleus. A minor fraction of the protein is translocated from the mitochondria to the nucleus, after cleavage of the targeting signal.
Tissue expression
Widely expressed, with highest levels in liver and kidney, followed by heart, spleen, skeletal muscle and placenta. In hemopoietic cells, expressed in dendritic cells, but not in monocytes, macrophages, granulocytes, nor in B and T lymphocytes.
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