Immunogen
The antiserum was produced against synthesized peptide derived from human ELOVL3. AA range:31-80
Specificity
ELOVL3 Polyclonal Antibody detects endogenous levels of ELOVL3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that belongs to the GNS1/SUR4 family. Members of this family play a role in elongation of long chain fatty acids to provide precursors for synthesis of sphingolipids and ceramides. [provided by RefSeq, Jul 2013],
Function
domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:May be involved in a membrane event related to cellular proliferation in brown adipose tissue. Could be implicated in synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
Protein name
Elongation of very long chain fatty acids protein 3
Other name
ELOVL3; CIG30; Elongation of very long chain fatty acids protein 3; 3-keto acyl-CoA synthase ELOVL3; Cold-inducible glycoprotein of 30 kDa; ELOVL fatty acid elongase 3; ELOVL FA elongase 3
Fields
>>Fatty acid elongation;>>Biosynthesis of unsaturated fatty acids;>>Metabolic pathways;>>Fatty acid metabolism
Human protein sequence Database
Q9HB03
Mouse protein sequence database
O35949
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Testis.
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