Molecular weight (DA)
50kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PLD4. AA range:457-506
Specificity
PC-PLD4 Polyclonal Antibody detects endogenous levels of PC-PLD4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,
Function
catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,
Protein name
Phospholipase D4
Other name
PLD4; C14orf175; Phospholipase D4; PLD 4; Choline phosphatase 4; Phosphatidylcholine-hydrolyzing phospholipase D4
Fields
>>Glycerophospholipid metabolism;>>Ether lipid metabolism;>>Metabolic pathways
Human protein sequence Database
Q96BZ4
Mouse protein sequence database
Q8BG07
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type II membrane protein . Nucleus . Early endosome . Cytoplasmic vesicle, phagosome . Activation of microglia induces translocation of PLD4 from the nucleus to the phagosomes. .
Tissue expression
B-cell,T-cell,
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