Molecular weight (DA)
30kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PGLS. AA range:191-240
Specificity
PGLS Polyclonal Antibody detects endogenous levels of PGLS protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate.,function:Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.,similarity:Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.,
Function
catalytic activity:6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate.,function:Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.,similarity:Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.,
Protein name
6-phosphogluconolactonase
Other name
PGLS; 6-phosphogluconolactonase; 6PGL
Fields
>>Pentose phosphate pathway;>>Metabolic pathways;>>Carbon metabolism
Human protein sequence Database
O95336
Mouse protein sequence database
Q9CQ60
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Brain,Cajal-Retzius cell,Fetal brain cortex,Uterus,
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