Molecular weight (DA)
44kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PIPOX. AA range:257-306
Specificity
PIPOX Polyclonal Antibody detects endogenous levels of PIPOX protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2).,catalytic activity:Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,function:Metabolizes sarcosine, L-pipecolic acid and L-proline.,similarity:Belongs to the MSOX/MTOX family.,subunit:Monomer.,
Function
catalytic activity:L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2).,catalytic activity:Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,function:Metabolizes sarcosine, L-pipecolic acid and L-proline.,similarity:Belongs to the MSOX/MTOX family.,subunit:Monomer.,
Protein name
Peroxisomal sarcosine oxidase
Other name
PIPOX; LPIPOX; PSO; Peroxisomal sarcosine oxidase; PSO; L-pipecolate oxidase; L-pipecolic acid oxidase
Fields
>>Glycine, serine and threonine metabolism;>>Lysine degradation;>>Metabolic pathways;>>Peroxisome
Human protein sequence Database
Q9P0Z9
Mouse protein sequence database
Q9D826
Rat protein sequence database
Cellular localization
Peroxisome .
Tissue expression
Expressed in the liver and kidney.
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