Molecular weight (DA)
52kD
Immunogen
The antiserum was produced against synthesized peptide derived from human UEVLD. AA range:141-190
Specificity
UEV3 Polyclonal Antibody detects endogenous levels of UEV3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Possible negative regulator of polyubiquitination.,similarity:Contains 1 UEV (ubiquitin E2 variant) domain.,similarity:In the C-terminal section; belongs to the LDH/MDH superfamily.,similarity:In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.,subunit:Homodimer.,tissue specificity:Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.,
Function
function:Possible negative regulator of polyubiquitination.,similarity:Contains 1 UEV (ubiquitin E2 variant) domain.,similarity:In the C-terminal section; belongs to the LDH/MDH superfamily.,similarity:In the N-terminal section; belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.,subunit:Homodimer.,tissue specificity:Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.,
Protein name
Ubiquitin-conjugating enzyme E2 variant 3
Other name
UEVLD; UEV3; Ubiquitin-conjugating enzyme E2 variant 3; UEV-3; EV and lactate/malate dehydrogenase domain-containing protein
Human protein sequence Database
Q8IX04
Mouse protein sequence database
Q3U1V6
Rat protein sequence database
Cellular localization
extracellular exosome,
Tissue expression
Colon, colon carcinoma cell lines, normal cervical epithelium, carcinomas of the uterine cervix and peripheral blood leukocytes.
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