Molecular weight (DA)
67kD
Immunogen
Purified Human serum albumin.
Specificity
This antibody detects endogenous levels of Serum Albumin and does not cross-react with related proteins.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016],
Function
caution:A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow.,disease:A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood [MIM:194470].,disease:Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.,function:Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the collo
Other name
ALB;ALBU_HUMAN;Albumin (32 AA);Albumin (AA 34);Albumin;Analbuminemia;Bisalbuminemia;Cell growth inhibiting protein 42;DKFZp779N1935;Dysalbuminemic hyperthyroxinemia;Growth inhibiting protein 20;HSA;Hyperthyroxinemia dysalbuminemic;PRO0883;PRO0903;PRO1341;PRO2044;PRO2619;Serum albumin.
Fields
>>Thyroid hormone synthesis
Human protein sequence Database
P02768
Mouse protein sequence database
P07724
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Plasma.
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