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EXOS2 rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-09070

  • 50UL $180 100UL $255
  • Delivery: In Stock

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Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human EXOS2 AA range: 90-140
Specificity
This antibody detects endogenous levels of EXOS2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
Function
function:Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity.,similarity:Contains 1 S1 motif domain.,subunit:Component of the exosome multienzyme ribonuclease complex composed of at least 11 proteins: EXOSC1/CSL4, EXOSC2/RRP4, EXOSC3/RRP40, EXOSC4/RRP41, EXOSC5/RRP46, EXOSC6/MTR3, EXOSC7/RRP42, EXOSC8/RRP43, EXOSC9/Scl-75, DIS3/RRP44, and EXOSC10/Scl-100 (only in the nuclear complex). Found in a mRNA decay complex with RENT1, RENT2 and RENT3B. Also associated with the GTPase Ran.,
Gene Name
EXOSC2 RRP4
Protein name
EXOS2
Abbreviation
EXOS2
Other name
Fields
>>RNA degradation
Human gene ID
23404
Human protein sequence Database
Q13868
Mouse gene ID
227715
Mouse protein sequence database
Q8VBV3
Rat gene ID
Rat protein sequence database
Cellular localization
Cytoplasm. Nucleus, nucleolus. Nucleus.
Tissue expression
Storage
-20°C/1 year

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EXOS2 rabbit pAb

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