Molecular weight (DA)
27kD
Immunogen
Recombinant Protein of EF-hand domain-containing protein D1
Specificity
The antibody detects endogenous EFHD1 proteins.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the EF-hand super family of calcium binding proteins, which are involved in a variety of cellular processes including mitosis, synaptic transmission, and cytoskeletal rearrangement. The protein encoded by this gene is composed of an N-terminal disordered region, proline-rich elements, two EF-hands, and a C-terminal coiled-coil domain. This protein has been shown to associate with the mitochondrial inner membrane, and in HeLa cells, acts as a novel mitochondrial calcium ion sensor for mitochondrial flash activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],
Function
similarity:Contains 2 EF-hand domains.,
Protein name
EF-hand domain-containing protein D1
Other name
EF-hand domain-containing protein D1 (EF-hand domain-containing protein 1) (Swiprosin-2)
Human protein sequence Database
Q9BUP0
Mouse protein sequence database
Q9D4J1
Rat protein sequence database
Cellular localization
Mitochondrion inner membrane .
Tissue expression
Brain,Eye,Heart,Hippocampus,Lung,Normal aorta,Placenta,
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