Molecular weight (DA)
100kD
Immunogen
The antiserum was produced against synthesized peptide derived from human KIF20A around the phosphorylation site of Ser528. AA range:501-550
Specificity
Phospho-KIF20A (S528) Polyclonal Antibody detects endogenous levels of KIF20A protein only when phosphorylated at S528.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 kinesin-motor domain.,
Function
function:Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 kinesin-motor domain.,
Protein name
Kinesin-like protein KIF20A
Other name
KIF20A; MKLP2; RAB6KIFL; Kinesin-like protein KIF20A; GG10_2; Mitotic kinesin-like protein 2; MKlp2; Rab6-interacting kinesin-like protein; Rabkinesin-6
Human protein sequence Database
O95235
Mouse protein sequence database
P97329
Rat protein sequence database
Cellular localization
Golgi apparatus . Cytoplasm, cytoskeleton, spindle . Localizes to the spindle midzone during anaphase and telophase. .
Tissue expression
Brain,Endothelial cell,Epithelium,Uterus,
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