Molecular weight (DA)
20kD
Immunogen
The antiserum was produced against synthesized peptide derived from human S100A16. AA range:19-68
Specificity
S-100A16 Polyclonal Antibody detects endogenous levels of S-100A16 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,
Function
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,
Protein name
Protein S100-A16
Other name
S100A16; S100F; AAG13; Protein S100-A16; Aging-associated gene 13 protein; Protein S100-F; S100 calcium-binding protein A16
Human protein sequence Database
Q96FQ6
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus, nucleolus . Cytoplasm . Primarily nucleolar. A high intracellular calcium level induces nucleolar exit and nucleocytoplasmic transport, whereas a low intracellular calcium level leads to nuclear translocation and accumulation within specific region of nucleoli (PubMed:17030513).
Tissue expression
Ubiquitous (PubMed:14684152). Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary (PubMed:14684152). Expressed in astrocytes (PubMed:17030513).
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