Immunogen
Synthetic peptide from human protein at AA range: 380-440
Specificity
The antibody detects endogenous Tubulin γ
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
Function
function:Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.,mass spectrometry: PubMed:11840567,similarity:Belongs to the tubulin family.,subunit:Interacts with GCP2 and GCP3. Interacts with B9D2.,
Protein name
Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
Abbreviation
Tubulin Gamma
Other name
Tubulin gamma-1 chain (Gamma-1-tubulin;Gamma-tubulin complex component 1;GCP-1)
Fields
>>Human papillomavirus infection
Human protein sequence Database
P23258
Mouse protein sequence database
P83887
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Localizes to mitotic spindle microtubules. .
Tissue expression
Mammary cancer,Skin,
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